Novel adjuvants and vaccine delivery systems
نویسندگان
چکیده
منابع مشابه
Novel Vaccine Adjuvants
Vaccines still remain the most successful method for protection and eradication against diseases. However, to avoid harmful effects associated with whole organism vaccines, new vaccine candidates are composed of parts of an organism, and therefore these are weakly immunogenic. Adjuvants are essential components of vaccines that nonspecifically stimulate the immune system, particularly the innat...
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Polymeric nanoand microparticles have recently been shown to possess significant potential as drug delivery systems. In particular, the use of biodegradable polymeric nanoparticles with entrapped antigens such as proteins, peptides, or DNA represents an exciting approach for controlling the release of vaccine antigens and optimizing the desired immune response via selective targeting of the ant...
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In the development of subunit vaccines with purified or recombinant antigens for cancer and infectious diseases, the design of improved and safe adjuvants able to efficiently target the antigen presenting cells, such as dendritic cells, represents a crucial challenge. Nanoparticle-based antigen delivery systems have been identified as an innovative strategy to improve the efficacy of subunit va...
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ژورنال
عنوان ژورنال: Veterinary Immunology and Immunopathology
سال: 1996
ISSN: 0165-2427
DOI: 10.1016/s0165-2427(96)05697-8